
The Most Important Research Trial Metric for Clinical Practice
I love key performance indicators (KPIs). Whether it’s in my practice, my finances, or my running. I believe the Number Needed to Treat (NNT) is the…
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by Kyle D Klute, OD, FAAO | May 25, 2025 | Follow the Science, Volume 3, Issue 2
I love key performance indicators (KPIs). Whether it’s in my practice, my finances, or my running. I believe the Number Needed to Treat (NNT) is the…
Read Moreby Kyle D Klute, OD, FAAO | Nov 17, 2024 | Follow the Science, Volume 2, Issue 4
in Part 3, we turn our focus to another, often overlooked, factor that influences clinical decision-making: the thorny topic of the pharmaceutical…
Read Moreby Kyle D Klute, OD, FAAO | Aug 20, 2024 | Follow the Science, Volume 2, Issue 3
Most of us want to be thoroughly research-based in our decisions for patients. However, if we reflected on our decision-making process, we would likely…
Read Moreby Kyle D Klute, OD, FAAO | May 10, 2024 | Follow the Science, Volume 2, Issue 2
In the context of our topic of evidence-based medicine, are our experiences and expert opinions a reliable source of evidence? If not, why not? If so, how much should we rely on experience and opinion (whether ours or others) to guide our clinical decision-making?
Read Moreby Kyle D Klute, OD, FAAO | Feb 22, 2024 | Follow the Science, Volume 2, Issue 1
How do we, as busy clinicians in the trenches of patient care, appraise and apply EBM to our practice? If you’ve read all that I’ve written on this topic…
Read Moreby Kyle D Klute, OD, FAAO | Nov 28, 2023 | Follow the Science, Volume 1, Issue 3
Deciding what something is not is just as important as knowing what something is Pertinent negatives in clinical practice help make deductive clinical…
Read Moreby Kyle D Klute, OD, FAAO | Aug 17, 2023 | Follow the Science, Volume 1, Issue 2
Imagine this: you are in your office scrolling through your unread emails and an email catches your eye with the subject line “kale consumption…
Read Moreby Kyle D Klute, OD, FAAO | May 1, 2023 | Follow the Science, Volume 1, Issue 1
How do we make good decisions for our patients? How do we decide which diagnosis is most appropriate? How do we decide which treatment plan provides the best possible outcome? More fundamentally, how do we decide while uncertain?
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